SCIENCE THAT MATTERS

Cyclophosphamide (the generic name for Cytoxan, Neosar)
By Tyla Teelucksingh

Initially used to treat Cancer, the drug has also been used to treat some autoimmune disorders.

It is a chemotherapy drug that works by slowing or stopping cell growth. It also works by decreasing the immune system's response to various diseases. Its use is becoming more common in autoimmune diseases where disease-modifying antirheumatic drugs (DMARDs) have been ineffective

Side effects may include pink/bloody urine, unusual decrease in the amount of urine, mouth sores, unusual tiredness or weakness, joint pain, easy bruising/bleeding, stopping of menstrual periods, existing wounds that are slow healing. 

Patients taking cyclophosphamide need to be closely monitored by their doctor.  It is important to weigh the beneficial effects as well as the risks involved in drug therapy. Doctors use the term "risk-benefit ratio" to describe the comparison of side effects to beneficial effects of medication. Discuss the risk-benefit ratio of your medications with your physician.